Advancing biological frontiers through gene editing and computational biology
29 & 30 October 2018
Malaysia Genome Institute (MGI)
PROGRAM SCHEDULE
DAY 1
29 October 2018
7.30 am : Registration
8.30 am : Opening Ceremony
8.45 am : Keynote address by Prof. Dr. Amir Feisal Merican Aljunid Merican
Title: "Bioinformatics: Current Trends, Challenges and Future Directions."
9.15 am : MASBIC Extraordinary General Meeting
10.45 am: Tea Break
11.00 am: Plenary lecture by Asssoc. Prof. Dr. Zeti Azura Mohamed Hussein
Title "Implementation of structural systems biology in modeling PCOS protein interaction network"
12.00 pm:
Parallel Workshop A (CRISPR/Cas9)
Principles of CRISPR/Cas9 Analysis
Parallel Workshop B (Molecular docking)
Principles of Molecular Docking Simulations
1.00 pm : Lunch and prayer
2.00 pm :
Parallel Workshop A (CRISPR/Cas9)
Hands-on Practicals:
I- Understanding the concept of single guide RNA (sgRNA)
II- Design primers and identify off-target regions using bioinformatics tools for CRISPR technologies
III- Viewing the construct
Parallel Workshop B
(Molecular Docking Simulations)
Hands-on Practicals:
I- Protein and Ligand preparation for docking simulation using Autodock
II- Docking simulation and Analysis
III- Visualization and H-bond analysis using Ligplot
4.00 pm : Parallel Wrap up and Discussion
5.00 pm : Tea Break
DAY 2
30 October 2018
8.30 am : Breakfast
9.00 am : Workshop B – Molecular Dynamics (MD) Simulation
Principles of Molecular Dynamics Simulation using GROMACS
Hands-on Practical:
IV- System preparation and Setting up Molecular Dynamics simulation
10.00 am : Tea Break
10.30 am : Workshop B – Molecular Dynamics (MD) Simulation
Hands-on Practicals:
V- Introduction to analysis tools for MD simulations and analysis of MD trajectory
VI- Molecular visualization using PyMol and VMD
12.00 pm : Lunch and prayer
2.00 pm : Workshop B – Molecular Dynamics (MD) Simulation
Hands-on Practical:
VII- Analysis of MD trajectory using GROMACS tools
4.00 pm : Wrap up and Discussion
5.00 pm : Tea Break and Disperse